Landmark Trials: Newer Insights in Lipid-lowering Therapy

Volume 1, Apr 2012

Gagandeep Singh Wander, MD, Manish Bansal, MD; DNB, Gurgaon, India.

Various randomized clinical trials have shown that statins reduce cardiovascular (CV) event rates. The guidelines for CV disease prevention have increasingly emphasized that lowering low-density lipoprotein cholesterol (LDL-C) levels with statins is the primary goal of lipidmodulating therapy. The effect of statins extends across all ranges of LDL-C with no obvious lower threshold for benefit. Various imaging studies have shown that statins not only slow the disease progression but may also lead to disease regression in some patients.  

Volume 1, Number 2, Page: 97-100